Summary

The corner spider bite is a frequent reason for consultation in the emergency services in Chile, which can produce a severe condition with cutaneous and systemic manifestations. In Chile, Loxocelles laeta is found mainly from Region I to Region VIII, although cases of loxocelism have been reported throughout the country. The venom of this spider has a cutaneous-necrotizing, hemolytic, vasculitic and coagulant effect. We can identify 3 types of loxocelism: necrotic cutaneous (80% of cases), edematous cutaneous (5%) and visceral cutaneous (10-15%). The latter has a lethality between 1 and 3% of the total cases of loxocelism, which depends largely on the early diagnosis and timely management. Any type of loxocelism should be controlled during the first 24 to 48 hours and watch for the appearance of symptoms and signs suggestive of visceral symptoms. There is no laboratory test to confirm the diagnosis, which are only markedly altered in visceral cases. Management of skin lesions is with local ice, anti-inflammatories, antihistamines and serial dressings. In the case of visceral loxocelism, the main treatment is supportive. Dapsone was a frequent indication in the past and is associated with serious adverse effects, the main one being exacerbation of hemolysis, so its use is not currently recommended. The anti-loxoceles serum does not have evidence that supports less severity or mortality of the condition.